ALL EXPERIMENTS IN SECURE ZONE - USE THE PASSWORD SUPPLIED TO YOU

1.  Install and practice Bioedit

2. Exploring major databses: Genbank/DDBJ/ENA(EMBL)

3. Understanding DNA / Protein coding system

4. Exploring genome-specific databses (Mouse / RAT/ Rice / Arabidopsis)

5. Dot-matrix comparison of sequences

6. Exploring protein sequence databases

7. Pairwise alignment of DNA / protein sequences using Needleman and Wunch algorithm

8. Pairwise alignment of DNA / protein sequences using Smith and Waterman algorithm

9. Exploring EST sequence and Clustering databases

10. Exploring gene databases

11. Exploring Genome variation resources

12. Database searching using rigorous Smith and Waterman algorithm

13. Understanding "Database searching by  FASA algorithm"

13. Understanding "Database searching by BLAST algorithm"

14.  ORF Finding using NCBI ORF finder and Bioedit

15. Microbial gene predition using Glimmer

16. Eukaryotic gene prediction using Genscan

17.  Functional annotation of predicted eukaryotic genes by homology searching protein and EST databases

18. Understanding multiple sequence alignment by Clustal-W tool (progressive alignment algorithm)

19. Editing and Analyzing multiple sequence alignment using Genedoc tool

20. Visualization of  protein structure: Download, install and practice Rasmol, the protein structure visualization tool

21. Prediction of protein secondary structures